Portage is a city in Kalamazoo County in the U.S. state of Michigan. The population was 46,292 in the 2010 census. It is the smaller of the two main cities included in the Kalamazoo-Portage Metropolitan Statistical Area, which has a population of 326,589 as of 2010.Portage is adjacent to the southern boundary of the City of Kalamazoo. The city was incorporated from the entirety of the former Portage Township on December 31, 1963.There are two public high schools in Portage, Portage Central and Portage Northern. The pharmaceutical company Pfizer also has manufacturing operations located there, which in recent years has caused much controversy due to layoffs. Stryker Corporation also has a large manufacturing presence in the city and is a worldwide leader in medical equipment, instruments and imaging technologies. Portage is also home to FEMA Corporation, a growing hydraulic valve manufacturing company.